Clioquinol (Iodochlorohydroxyquinoline)

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CAS No. 130-26-7
Mol. Formula  C9H5ClINO
Mol. Weight  305.5
Category Antiamoebic & Topical Anti-infective
Description Voluminous, spongy, yellowish-white to brownish-yellow powder, having slight characteristic odor. Darkens on exposure to light
Solubility Soluble in hot ethyl acetate and in hot glacial acetic acid. Practically insoluble in water and in alcohol.
Melting Point  About 180°C
Free iodine & iodide  Passes as per pharmacopoeia
Related substances  Passes as per pharmacopoeia
Residue on ignition  Not more than 0.5 % w/w Sulphated ash
Loss on drying  Not more than 0.5 % w/w
Assay  Between 97 and 101 % w/w

Uses: It has primarily been used as an anti-diarrheal medication. It is used in the treatment of acute and chronic amoebic dysentery, colitis, in GI track infections like amoebiasis, in dermatophytosis, sycosisbarbae, seborrhoeic dermatitis, infected eczema, furunculosis and pityriasisversicolor (athlete’s foot), Dermatitis, Impetigo, monilial and trichomonas vaginitis, giardiasis.

Standard Packing: 20 Kg Fibre Drum / HDPE Drum with double inner polythene bag.

pdf  Iodochlorohydroxyquinoline / Clioquinol MSDS